Rent A Car and Drive From San Francisco to Yosemite

Yosemite National Park can be an ideal destination to get away from bustling city life and enjoy nature while discovering America’s story. A rental car from a neighborhood Enterprise location in San Francisco might be the best option for your travel! Enterprise offers quick, convenient travel options so you can get on the road faster. With so many styles and options available, you’re sure to find the perfect rental car for your travels.

Drive time from San Francisco to Yosemite: approx. 3.5 hours (Driving Directions)

Distance: approx. 171 miles

Benefits of renting a car

Reduce wear-and-tear and/or mileage on your own vehicle
Choose from a variety of rental cars – like compacts, minivans or luxury SUVs – to fit your group’s needs
Select a style with extra cargo space – perfect for camping gear, hiking equipment or that last-minute RSVP
Enjoy add-ons such as car seats, GPS/navigational systems, ski racks and more

Popular Road Trip Cars

Take your pick from one of these classic road trip car options.

SUVs

Room for one more? With an SUV rental, you'll have room for baggage, souveneirs and last-minute additions.

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2-Door Jeep

2 is better than 1 with a 2-door jeep from Enterprise. Bring a friend, pick the playlist and get started on your next trip.

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4-Door Jeep

With more leg room and ample space for luggage, a 4-door Jeep is perfect for family outings.

View- 4-Door Jeeps

Convertible

With so many styles and options available, you’re sure to find the perfect rental car for your travels.

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San Francisco Drives and Road Trips

Map - Road Trip from Seattle to San Francisco

Road Trip from Seattle to San Francisco

Discover the Pacific Northwest through a road trip from Seattle to San Francisco.

Map - Los Angeles to San Francisco on Highway 1

Drive from LA to San Francisco on Highway 1

Discover the beauty of the California coast on a road trip from Los Angeles to San Francisco via the Pacific Coast Highway.

Map - San Francisco to Seattle – Napa and Inland Tour

Road Trip from San Francisco to Seattle – Napa and Inland Tour

Take your time to explore this unique part of the Pacific Northwest as you make stops in Napa Valley, Crater Lake, Portland and much more.

Map - Drive from San Francisco to Portland on Highway 101

Drive from San Francisco to Portland on Highway 101

With stunning forests and breathtaking coastlines, enjoy the beauty and adventure found along Highway 101 with this road trip itinerary from San Francisco to Portland.

Map - San Francisco to Seattle -3 Day Road Trip

Road Trip from San Francisco to Seattle in 3 Days

Go on a San Francisco to Seattle 3-day road trip with this comprehensive guide to two of the West Coast's most popular destinations.

Drive to a National or State Park Near San Francisco

Drive to a National or State Park Near San Francisco

Check out some of the top National & State Parks near San Francisco. Rent a car from one of our neighborhood locations and hit the road!

Map - San Francisco to Lake Tahoe

Road Trip From San Francisco to Lake Tahoe

If you are planning a San Francisco to Lake Tahoe road trip, look no further. Get tips, directions, distance and more with Enterprise.

Map - San Francisco to LA Along The PCH

Drive from San Francisco to LA Along The PCH

Take your time to explore this scenic stretch of the Pacific Coast Highway from San Francisco to Los Angeles.

Map - San Francisco to San Diego on Highway 99

Road Trip from San Francisco to San Diego on Highway 99

This road trip itinerary covers all the things to see and do along the drive from San Francisco to San Diego on Highway 99.

Map - San Diego to San Francisco via I-5

San Diego to San Francisco via I-5

Looking to get from San Diego to San Francisco using the fastest, most direct route? This is the road trip itinerary for you.

Map - San Diego to San Francisco

Road Trip from San Diego to San Francisco

Drive down the Pacific Coast Highway on your road trip from San Diego to San Francisco and enjoy scenic views, unforgettable beaches and more.

San Francisco to Yosemite

Looking to go from San Francisco to Yosemite? Driving may be your best option. Our neighborhood locations are open and ready to serve you with curbside pickup and enhanced vehicle cleaning procedures.

Rent a Car & Drive From Los Angeles to San Francisco

Los Angeles to San Francisco

Looking to go from Los Angeles to San Francisco? Driving may be your best option. Our neighborhood locations are open and ready to serve you with curbside pickup and modified cleaning procedures.

Map - San Francisco to Las Vegas

Road Trip from San Francisco to Las Vegas

Enjoy the drive through coastal cliffs, national forests and desert landscapes when you take a road trip from San Francisco to Las Vegas.

Map - Road Trip from Seattle to San Francisco
Map - Los Angeles to San Francisco on Highway 1
Map - San Francisco to Seattle – Napa and Inland Tour
Map - Drive from San Francisco to Portland on Highway 101
Map - San Francisco to Seattle -3 Day Road Trip
Drive to a National or State Park Near San Francisco
Map - San Francisco to Lake Tahoe
Map - San Francisco to LA Along The PCH
Map - San Francisco to San Diego on Highway 99
Map - San Diego to San Francisco via I-5
Map - San Diego to San Francisco
Drive from San Francisco to Yosemite
Rent a Car & Drive From Los Angeles to San Francisco
Map - San Francisco to Las Vegas

Driving Resources

Camping Checklists

The Enterprise App

Our iOS and Android apps make it easier than ever to manage reservations on the go.

Learn More & Download

Camping Checklists

Meet the Fleet

With so many styles and options available, you're sure to find the perfect rental for your travels.

View All Vehicles

Camping Checklists

Car Rental FAQs

Check out our FAQs for information on hours of operation, upcoming and existing reservations and more.